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PPAR agonists Peroxisome proliferator–activated receptors (PPARs) are transcription factors of nuclear hormone receptors with three subtypes PPAR-α, PPAR-γ, and PPAR-β/δ, which regulate lipid metabolism, energy homoeostasis, insulin sensitization, and glucose metabolism
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The team reports that LA3IK is the shortest peptide identified so far that can effectively inhibit EGF-driven tumorigenic signaling, highlighting its potential as a new precision approach for targeting advanced prostate cancer
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