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differently, in GSH, the peptide bond linking glutamate and cysteine is constituted by a γ-carbonyl group, which is resistant to the hydrolytic action of cellular peptidases
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Disruption of ciliary function by pyocyanin (see Section 2.1.1) further deteriorates mucociliary clearance of thickened mucus, leading to microbial-mediated acute exacerbation often seen in CF and COPD (177, 178)
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