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The decreased expression of transcription factors ETS1 and ETS2 by DR in WAT [7] may also function along with increased levels of ATF4 to decrease protein synthesis and stimulate longevity [340]
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Numerous saponins, including Paris saponin VII (137), ginsenoside Rb1 (138) and sodium aescinate (139), have been reported to inhibit the expression of P-gp and reverse tumor resistance
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