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Clinically preeclampsia is defined by American College of Obstetricians and Gynaecologists (ACOG) (2013) as a “syndrome characterized by both new-onset of hypertension plus new-onset proteinuria ≥ 300 mg/24 h after 20 weeks of gestation or, in the absence of proteinuria, hypertension in association with thrombocytopenia, impaired liver function, renal insufficiency, pulmonary edema, or new-onset cerebral or visual disturbances’’ [31]

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Although, elevated protein oxidation is usually associated with oxidative stress, recent findings reveal a fundamental role for this modification in cell signaling